UMBC Top Stories

News, research, and discoveries from our community

UMBC research team discovers promising molecular target for ovarian cancer treatment

Ovarian cancer is often diagnosed after it has already spread to other parts of the body, at which point the five-year survival rate is under 30 percent. Further complicating treatment, standard therapies cause substantial harm to healthy cells alongside cancerous ones. But what if ovarian cancer treatment could more specifically target cancerous cells, causing less harm to the rest of the body? New research from Achuth Padmanabhan’s lab offers hope in the form of a potential molecular target for new cancer drugs: an enzyme called USP15, which ovarian cancer cells appear to rely on more heavily than normal cells. Biological sciences Ph.D. student Ayokunnumi “Ayo” Ogunsanya led the work, which showed that lowering USP15 levels causes a constellation of effects that make it a prime target for new treatments.

Sep 24, 2026 • By Sarah Hansen, M.S. '15

Spring 2026 cover

UMBC Magazine

Spring 2026

On the Cover

Quilting is an entry point to storytelling, as UMBC CoLab students discovered. The artistic practice can make time stand still, be a window into the past, and inspire future quilters with possibilities.