ChemBiochem

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Deepak Koirala to explore how RNA viruses hijack cellular machinery, with eye to future drug treatments

/ 4 minutes of reading

RNA viruses cause many human diseases, but understanding of how they do it is poorly understood. Deepak Koirala is pursuing new research to figure out how they trick their host cells into making viral proteins. “It could be a new biological mechanism we’ve never seen before,” Koirala says. Continue Reading Deepak Koirala to explore how RNA viruses hijack cellular machinery, with eye to future drug treatments

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UMBC’s Arjun Kanjarpane and Anya Viswanathan receive prestigious Goldwater Scholarships

/ 7 minutes of reading

Both recipients have the potential to make a major impact in their fields and in people’s lives through their research. “We are delighted that UMBC has continued its impressive string of Goldwater awards for this year,” says April Householder “This indicates just how strong STEM education at UMBC is—indeed, it’s among the best in the country.” Continue Reading UMBC’s Arjun Kanjarpane and Anya Viswanathan receive prestigious Goldwater Scholarships

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Deepak Koirala to grow understanding of how enteroviruses replicate with $786K NSF CAREER Award

/ 6 minutes of reading

Diseases such as polio, the common cold, and meningitis are all caused by closely related enteroviruses and the way that these viruses multiply in the body is poorly understood. Deepak Koirala hopes to change that by investigating how the RNA structures within these viruses’ genetic material enable them to multiply. The answers could lead to drugs that attack specific mechanisms critical for viral replication, stopping these diseases in their tracks. Continue Reading Deepak Koirala to grow understanding of how enteroviruses replicate with $786K NSF CAREER Award

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UMBC’s Smith lab discovers enzyme ATE1’s role in cellular stress response, opening a door to new therapeutic targets

/ 5 minutes of reading

A new paper in Nature Communications illuminates how a previously poorly understood enzyme works in the cell. Many diseases are tied to chronic cellular stress, and Aaron T. Smith and colleagues discovered that this enzyme plays an important role in the cellular stress response. Better understanding how this enzyme functions and is controlled could lead to the discovery of new therapeutic targets for these diseases. Continue Reading UMBC’s Smith lab discovers enzyme ATE1’s role in cellular stress response, opening a door to new therapeutic targets

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Organ-on-a-chip models allow researchers to conduct studies closer to real-life conditions – and possibly grease the drug development pipeline

/ 5 minutes of reading

Bringing a new drug to market costs billions of dollars and can take over a decade. That contributes to today’s skyrocketing health care costs and creates significant obstacles to delivering new therapies to patients. But organ-on-a-chip models offer a better way, Chengpeng Chen argues. Continue Reading Organ-on-a-chip models allow researchers to conduct studies closer to real-life conditions – and possibly grease the drug development pipeline

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GRIT-X 2022 brings to life the “essence” of UMBC research and creative achievement

/ 5 minutes of reading

Amid a bustling day filled with Homecoming excitement, GRIT-X returned to UMBC this month for its sixth year, delivering a wide-ranging lineup of Retriever excellence in action. Held in the Fine Arts Recital Hall, this year’s GRIT-X was the first for new UMBC President Valerie Sheares Ashby. Enjoying one engaging talk after another, she deemed the event “the essence of UMBC.” Continue Reading GRIT-X 2022 brings to life the “essence” of UMBC research and creative achievement

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Creating new antiviral drugs: Katherine Seley-Radtke’s innovative “fleximer” research to receive $3.5M from NIH

/ 4 minutes of reading

“Many people in the antiviral field had been pushing for many years, warning people that this kind of viral pandemic could happen,” says Katherine Seley-Radtke. Thankfully, her decades of work put her in a strong position to contribute to a new surge of antiviral research. Continue Reading Creating new antiviral drugs: Katherine Seley-Radtke’s innovative “fleximer” research to receive $3.5M from NIH

Ten million reads: UMBC researchers hit milestone in sharing knowledge through The Conversation

/ 5 minutes of reading

Articles on The Conversation offer context to current events, explain natural phenomena, introduce new research in an accessible way, and more. “The Conversation helps us contribute to our public service mission as a public university,” says Vice President for Research Karl Steiner. “This milestone underscores the importance of academic researchers actively participating in the public discourse of complex issues.” Continue Reading Ten million reads: UMBC researchers hit milestone in sharing knowledge through The Conversation

Viral inventors: UMBC study finds virus DNA orchestrates a critical cellular pathway in bacteria

/ 7 minutes of reading

A protein produced by viral DNA is orchestrating the critical “SOS response” in a large group of bacterial species, according to a new study in Nucleic Acids Research. “It’s the SOS response because if the bacteria or virus doesn’t get it right, they die,” Ivan Erill says. Continue Reading Viral inventors: UMBC study finds virus DNA orchestrates a critical cellular pathway in bacteria

UMBC’s 2021 grads advance research with public impact—from disaster response to assistive tech

/ 11 minutes of reading

Students from across all three UMBC colleges are graduating this week having taken advantage of the unique undergraduate research opportunities and supportive mentorship UMBC offers. They’re poised to take their research to the next level and move on to new challenges through graduate school and careers. Continue Reading UMBC’s 2021 grads advance research with public impact—from disaster response to assistive tech

 

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