Several research groups in the department are
focused on the development and application of novel sensing and
imaging methodologies for biomedical, environmental and defense
related applications as well as for fundamental chemical and biochemical
analyses. To aid in these research efforts, a large number of
state-of-the-art and one-of-a-kind facilities are housed in the
newly renovated building, including continuous wave (CW), pulsed
and ultrafast laser sources for optical sensing and imaging and
a Faraday room and electrochemical workstations for sensitive
electrochemical analyses. Ongoing research projects and programs
within the department in the areas of sensors and imaging cover
a vast array of topics, ranging from the development of optical
nanosensors for single cell analyses to the study of excited state
chemical dynamics using ultrafast laser spectroscopy. In addition,
active programs in the fabrication and characterization of novel
fluorescent polymer based sensors for monitoring environmental
conditions (e.g., temperature, pressure, O2, etc.) and electrochemical
sensors for toxicological, forensic and pharmaceutical applications
also exist. In the area of chemical imaging, current research
projects include the development of minimally invasive optical
imaging techniques for brain tumor margining as well as the development
of novel nano-imaging probes for the visualization of individual
molecules and their dynamics.
Application of fluorescent live-cell imaging for human disease mechanisms
Coherent Back Scattered Spectroscopy
Development of optical nanosensors and nano-biosensors as well as chemical nano-imaging probes for cellular monitoring.
Synthesis of gadolinium-functionalized dendrons for use in MRI imaging.
Use of gold nanoparticles as CT contrast agents
Development of fluorescent polymers for thermal imaging in the visible spectral region.
Explosives analysis in environmental and physiological samples.
Development of new fluorescence probes for in vivo cancer bioimaging.
Development of nanoscale electrochemical sensors to monitor cell communication. Development of biocampatible copolymer sensing membranes for long-term in vivo sensing applications.