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Katherine Seley-Radtke
Associate Professor
Post-Doctoral Auburn University 1996; Ph.D. Auburn University 1996; B.A. University of South Florida 1992
Mosley, S. L.; Bakke, B. A.; Sadler, J. M.; Dorgan, K.; Zhou, Z. S.; Seley-Radtke, K. L. "Carbocyclic Pyrimidine Nucleosides as Inhibitors of S-Adenosylhomocysteine Hydrolase", Bioorganic Med. Chem. 2006 14, 7967-7971. Quirk, S.; Seley-Radtke, K.L. 'Purification, crystallization, and preliminary X-ray characterization of the human GTP fucose pyrophosphorylase' Acta Cryst. 2006, F62, 392-394. Quirk, S.; Seley, K. L. 'Identification of catalytic amino acids in the human GTP fucose pyrophosphorylase active site' Biochem. 2005, 44, 13172-13178. Quirk, S.; Seley, K. L. 'Substrate discrimination by the human GTP-fucose pyrophosphorylase' Biochem. 2005, 44, 10854-10863. Seley, K. L.; Salim, S.; Zhang, L.; O’Daniel, P. I. “Molecular Chameleons'. Design and Synthesis of A New Series of Flexible Nucleosides' J. Org. Chem. 2005, 70, 1612-1619. Seley, K. L.; Salim, S.; Zhang, L.;'Molecular Chameleons'. Design and Synthesis of C-4-Substituted Imidazole Fleximers Org, Lett. 2005, 7, 63-66. Schwimmer, L. J.; Rohatgi, P.; Azizi, B.; Seley, K. L.; Doyle, D. F. 'Creation and Discovery of Ligand-Receptor Pairs for Small Molecule Control of Transcription' Proc. Nat. Acad. Sci. 2004, 101, 14707-14712. Polak, M.; Seley, K. L.; Plavec, J. 'Conformational Properties of Novel Shaped Nucleosides – Fleximers' J. Am. Chem. Soc. 2004, 126, 8159-8166. Wallace, L. J. M.; Candlish, D.; Hagos, A.; Seley, K. L.; de Koning, H. P. 'Selective Transport of a New Class of Purine Antimetabolites by the Protozoan Parasite Trypanosoma Brucei' Nucleosides, Nucleotides and Nucleic Acids 2004, 23, 1441-1444. Seley, K. L.; Mosley, S. L.; Xing, F. 'Carbocyclic Isoadenosine Analogues of Neplanocin A' Org. Lett., 2003, 5, 4401-4403. Seley, K. L.; Quirk, S.; Salim, S.; Zhang, L.; Hagos, A. 'Unexpected Inhibition of S-Adenosyl-L-homocysteine Hydrolase by a Guanosine Nucleoside' Bioorg. Med. Chem. Lett. 2003, 13, 1985-1988. Seley, K. L.; Zhang, L.; Hagos, A.; Quirk, S. ''Fleximers'. Design and Synthesis of A New Class of Novel Shape-Modified Nucleosides' J. Org. Chem., 2002, 67, 3365-3373. Seley, K. L. 'Tricyclic Nucleosides Revisited' in Recent Advances in Nucleosides: Chemistry and Chemotherapy, pg. 299-326, C.K. Chu, Ed. Elsevier Science, 2002. Seley, K. L.; Zhang, L. Hagos, A. ''Fleximers'. Design and Synthesis of Two Novel Split Nucleosides' Org. Lett., 2001, 3, 3209-3210. Seley, K. L.; Januszczyk, P.; Hagos, A.; Zhang, L.; Dransfield, D.T. 'Synthesis and Antitumor Activity of Thieno-Separated Tricyclic Purines' J. Med. Chem., 2000, 43, 4877-4883.
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