UMBC An Honors University in Maryland
UMBC Biological Sciences
Maricel Kann
Contact Information
Office: BS 116
Phone: 410-455-2258
Maricel Kann
Associate Professor
Postdoctorate, National Center for Biotechnology Information, NIH, 2007; Ph.D., University of Michigan, Ann Arbor, 2001
Selected publications

Nehrt, NL, Peterson, T, Park, D & Kann, MG (2012). Domain landscapes of somatic mutations in cancer. BMC genomics 13 Suppl 4, S9.
[Abstract] [Text] [PDF]

Peterson, TA, Nehrt, NL, Park, D & Kann, MG. (2012) Incorporating molecular and functional context into the analysis and prioritization of human variants associated with cancer. Journal of the American Medical Informatics Association : JAMIA 19, 275-283.
[Abstract] [Text] [PDF]

Regan, K, Wang, K, Doughty, E, Li, H, Li, J, Lee, Y, Kann, MG & Lussier, YA. (2012) Translating Mendelian and complex inheritance of Alzheimer's disease genes for predicting unique personal genome variants. Journal of the American Medical Informatics Association : JAMIA 19, 306-316.
[Abstract] [Text] [PDF]

Capriotti, E, Nehrt, NL, Kann, MG & Bromberg, Y. (2012) Bioinformatics for personal genome interpretation. Briefings in bioinformatics, 13(4):495-512.
[Abstract] [Text] [PDF]

Doughty, E, Kertesz-Farkas, A, Bodenreider, O, Thompson, G, Adadey, A, Peterson, T & Kann, MG.(2011) Toward an automatic method for extracting cancer- and other disease-related point mutations from the biomedical literature. Bioinformatics (Oxford, England) (27), 408-415.
[Abstract] [Text] [PDF]

 Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G. (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.
[Abstract] [Text] [PDF]

Carroll, HD, Kann, MG, Sheetlin, SL & Spouge, JL. (2010) Threshold Average Precision (TAP-k): A Measure of Retrieval Designed for Bioinformatics. Bioinformatics 26 (14), 1708-1713.
[Abstract] [PDF]

Mort, M., Evani, U.S., Krishnan, V.G., Kamati, K.K., Baenziger, P.H., Bagchi, A., Peters, B.J., Sathyesh, R., Li, B., Sun, Y., Xue, B., Shah, N.H., Kann, M.G., Cooper, D.N., Radivojac, P. & Mooney, S.D. (2010)  In silico functional profiling of human disease-associated and polymorphic amino acid substitutions. Hum Mutat 31, 335-346.
[Abstract] [Text] [PDF]

Kann, M.G. (2010)  Advances in translational bioinformatics: computational approaches for the hunting of disease genes. Briefings in bioinformatics 11, 96-110.
[Abstract] [Text] [PDF]

Alkan, C., Brudno, M., Eichler, E.E., Kann, M.G. & Sahinalp, S.C. (2010) PERSONAL GENOMICS - Session Introduction. Pac Symp Biocomput 15, 302-304.
[Abstract] [Text] [PDF]

Kann, M. G., Shoemaker, B. A., Panchenko, A. R. & Przytycka, T. M. (2009). Correlated evolution of interacting proteins: looking behind the mirrortree. J Mol Biol 385, 91-8.

Radivojac, P., Baenziger, P. H., Kann, M. G., Mort, M. E., Hahn, M. W. & Mooney, S. D. (2008). Gain and loss of phosphorylation sites in human cancer. Bioinformatics 24, i241-7.

Singh, A., Olowoyeye, A., Baenziger, P.H., Dantzer, J., Kann, M.G., Radivojac, P., Heiland, R. & Mooney, S.D. (2008)MutDB: update on development of tools for the biochemical analysis of genetic variation. Nucleic acids research 36, D815-819


[Abstract] [Text] [PDF]

Kann, M. G. (2007). "Protein interactions and disease: computational approaches to uncover the etiology of diseases." Brief Bioinform, 8(5):333-46. Epub 2007 Jul 16

[Abstract] [Text] [PDF]

Kann, M. G., S. L. Sheetlin, Y. Park, et al. (2007). "The identification of complete domains within protein sequences using accurate E-values for semi-global alignment." Nucleic Acids Res 35(14): 4678-85.
[Abstract] [Text] [PDF]

Kann, M. G., R. Jothi, P. F. Cherukuri, et al. (2007). "Predicting protein domain interactions from coevolution of conserved regions." Proteins 67(4): 811-20
[Abstract] [Text] [PDF]

Valdivia-Granada, W. A., M. G. Kann and J. Malaga (2007). "Transcriptional Interactions during smallpox infection and identification of early infection biomarkers." Pac Symp Biocomput.: 100-111.
[Abstract] [PDF]

Kann, M. G., P. A. Thiessen, A. R. Panchenko, et al. (2005). "A structure-based method for protein sequence alignment." Bioinformatics 21(8): 1451-6.
[Abstract] [Text] [PDF]

Jothi, R., M. G. Kann and T. M. Przytycka (2005). "Predicting protein-protein interaction by searching evolutionary tree automorphism space." Bioinformatics 21 Suppl 1: i241-i250
[Abstract] [PDF]

Marino-Ramirez, L., M. G. Kann, B. A. Shoemaker, et al. (2005). "Histone structure and nucleosome stability." Expert Rev Proteomics 2(5): 719-29.
[Abstract] [Text] [PDF]

Valdivia-Granada, W. A., C. D. Keating, M. Kann, et al. (2005). Detection of Encephalic and Hemorrhagic Viruses: Integration of Micro and Nano-fabrication with Computational Tools. IEEE.International Conference on MEMS, NANO and Smart Systems, IEEE.
[Abstract]

Kann, M. and R. A. Goldstein (2004). OPTIMA: A new score function for the detection of remote homologs. in Mathematical Methods for Protein Structure Analysis and Design. Lectures Notes in Computer Science. Springer-Verlag. Heidelberg: 99-107.
[Abstract] [PDF]

Kann, M. G. and R. A. Goldstein (2002). "Performance evaluation of a new algorithm for the detection of remote homologs with sequence comparison." Proteins 48(2): 367-76.
[Abstract] [Text] [PDF]

Kann, M., B. Qian and R. A. Goldstein (2000). "Optimization of a new score function for the detection of remote homologs." Proteins 41(4): 498-503.
[Abstract] [Text] [PDF]

Kann, M. and R. A. Goldstein (2000). Optimizing for Success: A new score function for distantly related proteins. Fourth annual international conference on computational molecular biology (RECOMB). Tokyo, Japan, ACM: 177-182
[Abstract] [PDF]