UMBC An Honors University in Maryland
UMBC Biological Sciences
Philip Farabaugh
Contact Information
Office: BS 478
Phone: 410-455-3018
Philip Farabaugh
Professor and Chair
Postdoctoral, Genetics, Cornell University, 1981; Ph.D., Biochemistry, Harvard University, 1978; B.A., Biology, University of California, San Diego, 1972
Selected publications

Kramer EB, Vallabhaneni H, Mayer LM, Farabaugh PJ. 2010. A comprehensive analysis of translational missense errors in the yeast Saccharomyces cerevisiae. RNA [Epub ahead of print].

[Abstract] [PDF]

Dakshinamurthy A, Nyswaner KM, Farabaugh PJ, Garfinkel DJ. BUD22 affects Ty1 retrotransposition and ribosome biogenesis in Saccharomyces cerevisiae. Genetics. 2010 [Epub ahead of print]
[Abstract] [PDF]

Vallabhaneni H, Farabaugh PJ.  Accuracy modulating mutations of the ribosomal protein S4-S5 interface do not necessarily destabilize the rps4-rps5 protein-protein interaction. RNA. 2009 15:1100-1109.
[Abstract] [PDF]

Vallabhaneni H, Fan-Minogue H, Bedwell DM, Farabaugh PJ. Connection between stop codon reassignment and frequent use of shifty stop frameshifting. RNA 2009 15:889-897.
[Abstract] [PDF]

Botlagunta M, Vesuna F, Mironchik Y, Raman A, Lisok A, Winnard P Jr, Mukadam S, Van Diest P, Chen JH, Farabaugh P, Patel AH, Raman V. Oncogenic role of DDX3 in breast cancer biogenesis. Oncogene. 2008 27:3912-3922.
[Abstract] [Text] [PDF]

Guarraia C, Norris L, Raman A, Farabaugh PJ. Saturation mutagenesis of a +1 programmed frameshift-inducing mRNA sequence derived from a yeast retrotransposon. RNA 2007 13:1940-1947.
[Abstract] [PDF]

Taliaferro DL, Farabaugh PJ. Testing constraints on rRNA bases that make nonsequence-specific contacts with the codon•anticodon complex in the ribosomal A site. RNA. 2007 13:1279-1286.
[Abstract] [Text] [PDF]

Taliaferro D, Farabaugh PJ. An mRNA sequence derived from the yeast EST3 gene stimulates programmed +1 translational frameshifting. 2007 RNA 13:606-613.
[Abstract] [PDF]

Kramer EB, Farabaugh PJ. The frequency of translational misreading errors in E. coli is largely determined by tRNA competition. RNA 2007 13:87-96.
[Abstract] [PDF]

Farabaugh PJ, Kramer E, Vallabhaneni H, Raman A. Evolution of +1 programmed frameshifting signals and frameshift-regulating tRNAs in the order Saccharomycetales. J Mol Evol. 2006 63:545-561.
[Abstract] [PDF]

Raman A, Guarraia C, Taliaferro D, Stahl G, Farabaugh PJ. An mRNA sequence derived from a programmed frameshifting signal decreases codon discrimination during translation initiation. RNA. 2006 12:1154-1160.
[Abstract] [PDF]

Salas-Marco J, Fan-Minogue H, Kallmeyer AK, Klobutcher LA, Farabaugh PJ, Bedwell DM. Distinct paths to stop codon reassignment by the variant-code organisms Tetrahymena and Euplotes. Mol Cell Biol. 2006 26:438-447.
[Abstract] [Text] [PDF]

Stahl G, Salem SN, Chen L, Zhao B, Farabaugh PJ. Translational accuracy during exponential, postdiauxic, and stationary growth phases in Saccharomyces cerevisiae. Eukaryot Cell. 2004 3:331-338.
[Abstract] [PDF]

Stahl G, Ben Salem S, Li Z, McCarty G, Raman A, Shah M, Farabaugh PJ. Programmed +1 translational frameshifting in the yeast Saccharomyces cerevisiae results from disruption of translational error correction. Cold Spring Harb Symp Quant Biol. 2001 66:249-258.

Klobutcher LA, Farabaugh PJ. Shifty ciliates: frequent programmed translational frameshifting in euplotids. Cell. 2002 111:763-766.
[Abstract] [PDF]